 Select the route of administration which carries the highest risk of adversely affecting vital functions:

Which of the following is a source for obtaining drugs-

The science which is concerned with the study of mechanism of action of drug and pharmacological effects produced on the human body is known as-

 The rate of absorption of a drug is affected by

 Putting a drug in liquid form into a body cavity or body orifice, is known as-

The study of absorption, distribution, metabolism and excretion of drug is known as-  

Application of the drug to the skin usually by a friction is known as-

Nitroglycerine is administered by which route

Drugs are excreted from the body through-

 Alkalinization of urine hastens the excretion of:

 Majority of drugs cross biological membranes primarily by:

 Is dependent upon metabolic activity of the cell

 Is competitively inhibited by chemically related drugs

Is affected by extent of ionization of drug mole- cules.

Diffusion of drugs across cell membrane

Which of the following is a weakly acidic drug:

 The most important factor which governs diffusion of drugs across capillaries other than those in the brain is:

The substances produced by or derived from living organisms that are used to kill bacteria or prevent their multiplication is called-

Active transport of a substance across biological membranes has the following characteristics except

% of administered dose that reaches systemic circulation in the unchanged 

 Ratio of orally administered drug to that excreted in the faeces.

Ratio of drug excreted unchanged in urine to that excreted as metabolites

Bioavailability of drug refers to:

Which of the following drugs is most likely to be absorbed from the stomach:

Complexing with the other drug in the intestinal lumen

Tricyclic antidepressants can alter the oral absorption of many drugs by:

The science which deals with the drug and their action on human body is called-

Which of the following is a complication of injections

In an unconscious patient which is the preferred route of drug administration

 Which vitamin is also known as anti-sterility vitamin

Which of the following is not a part of syringe

 5% dextrose in normal saline (NS) is

Increase heart rate and cardiac muscle contractions

 Cardiotonics are the drugs used to-

Galactogouge is the drug which-

Drugs which dilate the blood vessels and used to lower blood pressure

Mydriatics are drugs which

 In ‘Intra-articular’ route of drug administration injection is given into

Reduce muscle tone and cause muscle relaxation

Hypnotics are the drug which

Drugs which are used to prevent or relieve nausea and vomiting-

 When the drug is introduced in the bone h- marrow, this route is called-

Drugs that meet the priority health care needs of the population

Drugs that must be present in the emergency bag of a doctor

 Drugs that are listed in the pharmacopoia of a country

'Essential drugs' are:

Drug administered through the following route is most likely to be subjected to first-pass metabolism

A drug needed for treatment or prevention of a rare disease

 A drug which acts on Orphan in receptors

 An 'orphan drug' is:

Carries greater risk of anaphylactic reaction

 Compared to subcutaneous injection, the intramuscular injection of drugs:

In addition to slow intravenous infusion, which of the following routes of administration allows for titration of the dose of a drug with the response:

Which of the following drugs is administered by intra- nasal spray/application for systemic action

They produce high peak plasma concentration of the drug

They produce smooth and non fluctuatingplasma concentration of the drug 

They minimise interindividual variations in  the achieved plasma drug conc.

They avoid hepatic first-pass metabolism of the drug

Transdermal drug delivery systems offer the following advantages except:

Induration of the skin and scar formation

 Repeated injections on the same spot can cause-

Aspirin has analgesic, antipyretic and anti- inflammatory actions.

 Aspirin can cause gastric ulceration and GI bleeding

 Aspirin increases platelet aggregation and help in blood coagulation

 Aspirin provides symptomatic relief in rheumatoid arthritis

Which of the following statement is not true about aspirin (Acetyl salicylic acid)-

Each 100 ml contains 5 gms glucose and 5 gm sodium chloride

 Each 100 ml. contains 5 gms. glucose and 0.9 gm, sodium chloride.

 Each 100 ml contains 5 gms. glucose and 0.4 gms sodium chloride.

Each 100 ml contains 0.5 gms. glucose ana 0.9 gm. sodium chloride

5% glucose saline means-

) To select the site quickely and accurately.